Eric Demoncheaux
e_demoncheaux@yahoo.fr
Address
Battle Abbey School
Battle
East Sussex
TN33 OAD
England
Interests
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Nitrite chemistry and biology
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Role of whole body nitric oxide production in diseases
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New sensitive techniques to measure nitric oxide and its derivatives
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Use of Information and Communication Technology (ICT) to support Science Education
Qualifications
- 2006: Post-Graduate Certificate of Education (PGCE), Anglia Ruskin University, Chelmsford, England
- 1998: Ph.D. ‘Physico-chemical properties of nitrogen monoxide: implications for its role as a vasodilator’ (Advisors: Dr. Higenbottam, Dr. Constable, Pr. Davies ), Anglia Polytechnic University and University of Cambridge, Cambridge, England
- 1992: B.Sc. (Hons. 2:1), Analytical Sciences, University of Greenwich, London, England
- 1991: Diplôme Universitaire de Technologie (Chimie), Institut Universitaire de Béthune, Artois University, France
Career History
I entered into the field of “nitric oxide chemistry and biology” when I started my PhD in Cambridge under the supervivion of Tim Higenbottam, Ed Constable and Mike Davies. My work focused on the development of specific and sensitive techniques to measure NO in biological milieu with a particular emphasis on its rate of reactions with biologically important molecules.
I then moved to Sheffield where I designed and conducted various studies including patients with pulmonary hypertension and portal hypertension where the L-arginine/NO pathway plays a critical role in the aetiology and management of these conditions. I also significantly contributed to Framework V projects PHIL (www.phil.ens.fr) and COPHIT (click here) and submitted two patents .
After 7 years teaching at University, I felt that I would best contribute to student ’s education at Secondary level where the uptake of Science subjects has steadily been declining over the last 10 years. I now work as a Science teacher at Battle Abbey School where I am developing and implementing novel teaching methods using ICT to support Science education and empower pupils to develop their own learning strategies. I recently took part in a High School Teacher programme at CERN with the aim to develop novel "qualitative" teaching strategies (click here).
I also work as Consultant for Futurelab (www.futurelab.org.uk) and have recently helped design a new interactive game to enhance visits to London Science Museum. Finally, I am a Council member of « Au Pas de Cal’Ane » (www.anes.ht.st) which is an Association aiming to help re-insertion of youngsters with special needs using pioneering "therapeutic" techniques.
Publications
- Demoncheaux E, Elphick D, Durner M, Higgins G, Crowther D, Williams E, Higenbottam T, Gleeson D (2006) Conservation of whole body nitric oxide production in human alcoholic liver disease: implications for nitric oxide production. Scandinavian Journal of Gastroenterology. 820-5.
- Demoncheaux E, Higenbottam T, Kiely D, Wong JM, Wharton S, Varcoe R, Siddons T, Spivey A, Hall K, Gize A (2005) Decreased whole body nitric oxide production in patients with primary pulmonary hypertension. Journal of Vascular Research. 42: 133-6.
- Demoncheaux E, Higenbottam T and Gleeson D. (2003) The disturbance of metabolism of oxides of nitrogen in liver disease: exhaled nitric oxide as a measure of severity. In Disease Markers in Exhaled Breath. (Eds. Marczin N, Kharitonov S, Yacoub M, Barnes PJ), pp 445-462, Marcel Dekker Inc., New York.
- Demoncheaux E, Foster P, Borland C, Smith A, Higenbottam T, Davies M (2003). Determination of trace concentrations of dissolved nitric oxide in a biological buffer. The Analyst. 128:1281-1285.
- Demoncheaux E, Higenbottam T, Foster P, Borland C, Smith A, Marriott H, Akamine S, Bee D, Davies M (2002). Circulating nitrite anions are a directly acting vasodilator and are donors for nitric oxide. Clinical Science (London) 102: 77-83 and 103: 108-110.
- Demoncheaux E, Maniscalco M, Roe S, Cremona G and Higenbottam T (1996). Exhaled NO, ideas on its origin and physiological meaning. In Nitric Oxide and Oxygen Radicals in the Pulmonary Vasculature. (Ed. Weir E, Archer S and Reeves D), pp 427-446, Futura Edition, New York.